Version 5.4
Homo sapiens Protein: MIER2
Summary
InnateDB Protein IDBP-12102.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIER2
Protein Name mesoderm induction early response 1, family member 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000264819
InnateDB Gene IDBG-12100 (MIER2)
Protein Structure
UniProt Annotation
Function Transcriptional repressor. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00512, ECO:0000255PROSITE-ProRule:PRU00624}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000949 ELM2 domain
IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like
PFAM PF01448
PF00249
PRINTS
PIRSF
SMART SM00717
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N344
PhosphoSite PhosphoSite-Q8N344
TrEMBL
UniProt Splice Variant
Entrez Gene 54531
UniGene Hs.101891
RefSeq NP_060020
HUGO HGNC:29210
OMIM
CCDS CCDS32855
HPRD 11130
IMGT
EMBL AB033019 BC028203
GenPept AAH28203 BAA86507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca