InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NRIP2

Summary

InnateDB Protein

IDBP-12422.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NRIP2

Protein Name

nuclear receptor interacting protein 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000337501

InnateDB Gene

IDBG-12420 (NRIP2)

Protein Structure

UniProt Annotation

Function

Down-regulates transcriptional activation by nuclear receptors such as NR1F2. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004190	aspartic-type endopeptidase activity
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006508	proteolysis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR019103 Aspartic peptidase, DDI1-type
IPR021109 Aspartic peptidase domain

PFAM

PF09668

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9BQI9

PhosphoSite

PhosphoSite-

TrEMBL

F5H2G5

UniProt Splice Variant

Entrez Gene

83714

UniGene

Hs.530816

RefSeq

NP_113662

HUGO

HGNC:23078

OMIM

CCDS

CCDS8514

HPRD

14839

IMGT

EMBL

AC005841 AK098063 AK300944 AL136557 BC036063 BC131562 CH471116

GenPept

AAH36063 AAI31563 BAG53573 BAG62573 CAB66492 EAW88888