InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGHG2

Summary

InnateDB Protein

IDBP-124370.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGHG2

Protein Name

immunoglobulin heavy constant gamma 2 (G2m marker)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000374987

InnateDB Gene

IDBG-124366 (IGHG2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003823	antigen binding
GO:0005515	protein binding

Biological Process

GO:0006956	complement activation
GO:0006958	complement activation, classical pathway
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07654
PF08205

PRINTS

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P01859

PhosphoSite

PhosphoSite-P01859

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:5526

OMIM

147110

CCDS

HPRD

IMGT

IGHG2

EMBL

AL928742 J00230

GenPept

AAB59393