Version 5.4
Mus musculus Protein: C6
Summary
InnateDB Protein IDBP-127940.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol C6
Protein Name complement component 6
Synonyms AW111623;
Species Mus musculus
Ensembl Protein ENSMUSP00000022788
InnateDB Gene IDBG-127938 (C6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001970 positive regulation of activation of membrane attack complex
GO:0006955 immune response
GO:0045766 positive regulation of angiogenesis
GO:0045917 positive regulation of complement activation
Cellular Component
GO:0005579 membrane attack complex
Protein Structure and Domains
PDB ID MGI:88233
InterPro IPR000436 Sushi/SCR/CCP
IPR000884 Thrombospondin, type 1 repeat
IPR001862 Membrane attack complex component/perforin/complement C9
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR020864 Membrane attack complex component/perforin (MACPF) domain
PFAM PF00084
PF00090
PF00057
PF01823
PRINTS PR00764
PR00261
PIRSF
SMART SM00032
SM00209
SM00192
SM00457
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q91X70
UniProt Splice Variant
Entrez Gene 12274
UniGene Mm.20247
RefSeq XP_006520020
MGI ID
MGI Symbol C6
OMIM
CCDS CCDS37025
HPRD
IMGT
EMBL AC102033 AC117588 AK041057 BC011251 CH466581
GenPept AAH11251 BAC30803 EDL03393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca