InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pon2

Summary

InnateDB Protein

IDBP-128086.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pon2

Protein Name

paraoxonase 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000062670

InnateDB Gene

IDBG-128084 (Pon2)

Protein Structure

UniProt Annotation

Function

Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004064	arylesterase activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006979	response to oxidative stress
GO:0019439	aromatic compound catabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0005886	plasma membrane
GO:0043231	intracellular membrane-bounded organelle