InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sdr16c5

Summary

InnateDB Protein

IDBP-128471.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sdr16c5

Protein Name

short chain dehydrogenase/reductase family 16C, member 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046298

InnateDB Gene

IDBG-128469 (Sdr16c5)

Protein Structure

UniProt Annotation

Function

Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004745	retinol dehydrogenase activity
GO:0016491	oxidoreductase activity

Biological Process

GO:0008152	metabolic process
GO:0042572	retinol metabolic process
GO:0042574	retinal metabolic process
GO:0043616	keratinocyte proliferation
GO:0055114	oxidation-reduction process