InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Impad1

Summary

InnateDB Protein

IDBP-128521.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Impad1

Protein Name

inositol monophosphatase domain containing 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000082013

InnateDB Gene

IDBG-128519 (Impad1)

Protein Structure

UniProt Annotation

Function

May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. {ECO:0000269PubMed:18695242}.

Subcellular Localization

Golgi apparatus {ECO:0000269PubMed:18695242}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008254	3'-nucleotidase activity
GO:0008441	3'(2'),5'-bisphosphate nucleotidase activity
GO:0008934	inositol monophosphate 1-phosphatase activity
GO:0046872	metal ion binding
GO:0052832	inositol monophosphate 3-phosphatase activity
GO:0052833	inositol monophosphate 4-phosphatase activity

Biological Process

GO:0001501	skeletal system development
GO:0001958	endochondral ossification
GO:0002063	chondrocyte development
GO:0006021	inositol biosynthetic process
GO:0009791	post-embryonic development
GO:0016311	dephosphorylation
GO:0030204	chondroitin sulfate metabolic process
GO:0042733	embryonic digit morphogenesis
GO:0046854	phosphatidylinositol phosphorylation