InnateDB Protein
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IDBP-128589.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tmem106b
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Protein Name
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transmembrane protein 106B
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Synonyms
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2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000031556
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InnateDB Gene
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IDBG-128587 (Tmem106b)
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Protein Structure
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Function |
Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching (By similarity). {ECO:0000250}.
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Subcellular Localization |
Late endosome membrane {ECO:0000250}; Single-pass type II membrane protein. Lysosome membrane {ECO:0000250}; Single-pass type II membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1919150
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InterPro |
IPR009790
Protein of unknown function DUF1356, TMEM106
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PFAM |
PF07092
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q80X71
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PhosphoSite |
PhosphoSite-Q80X71
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TrEMBL |
D3Z6E0
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UniProt Splice Variant |
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Entrez Gene |
71900
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UniGene |
Mm.409629
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RefSeq |
NP_082268
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MGI ID |
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MGI Symbol |
Tmem106b
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OMIM |
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CCDS |
CCDS19914
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HPRD |
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IMGT |
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EMBL |
AC136455
AK009646
BC050246
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GenPept |
AAH50246
BAB26411
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