InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Msgn1

Summary

InnateDB Protein

IDBP-128724.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Msgn1

Protein Name

mesogenin 1

Synonyms

pMsgn1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000055001

InnateDB Gene

IDBG-128722 (Msgn1)

Protein Structure

UniProt Annotation

Function

Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation. {ECO:0000269PubMed:10837126, ECO:0000269PubMed:11124811}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001756	somitogenesis
GO:0006351	transcription, DNA-templated
GO:0007379	segment specification
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter