Version 5.4
Mus musculus Protein: Tox
Summary
InnateDB Protein IDBP-128781.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tox
Protein Name thymocyte selection-associated high mobility group box
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037966
InnateDB Gene IDBG-128779 (Tox)
Protein Structure
UniProt Annotation
Function May play a role in regulating T-cell development. {ECO:0000269PubMed:11850626}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267, ECO:0000269PubMed:11850626}.
Disease Associations
Tissue Specificity Detected in brain, liver, small intestine, spleen, stomach, testis and thymus. {ECO:0000269PubMed:11850626}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2181659
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q66JW3
PhosphoSite PhosphoSite-Q66JW3
TrEMBL
UniProt Splice Variant
Entrez Gene 252838
UniGene Mm.481047
RefSeq NP_663757
MGI ID 2CO9
MGI Symbol Tox
OMIM
CCDS CCDS17953
HPRD
IMGT
EMBL AF472514 AK029694 AK038671 AK051947 BC080732
GenPept AAH80732 AAL78656 BAC26568 BAC30091 BAC34818

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca