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InnateDB Protein
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IDBP-129491.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Chst9
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Protein Name
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carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
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Synonyms
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5430438D01Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000049975
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InnateDB Gene
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IDBG-129489 (Chst9)
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Protein Structure
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| Function |
Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta.
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| Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Highly expressed in kidney and pituitary gland. {ECO:0000269PubMed:12944377}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
1 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0001537
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N-acetylgalactosamine 4-O-sulfotransferase activity
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GO:0008146
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sulfotransferase activity
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1918617
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| InterPro |
IPR005331
Sulfotransferase
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| PFAM |
PF03567
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q76EC5
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
71367
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| UniGene |
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| RefSeq |
NP_951010
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| MGI ID |
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| MGI Symbol |
Chst9
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| OMIM |
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| CCDS |
CCDS29074
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| HPRD |
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| IMGT |
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| EMBL |
AB106879
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| GenPept |
BAC87754
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Version 5.4