InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vasn

Summary

InnateDB Protein

IDBP-129846.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vasn

Protein Name

vasorin

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000045162

InnateDB Gene

IDBG-129844 (Vasn)

Protein Structure

UniProt Annotation

Function

May act as an inhibitor of TGF-beta signaling. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0050431	transforming growth factor beta binding

Biological Process

GO:0010719	negative regulation of epithelial to mesenchymal transition
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0071456	cellular response to hypoxia
GO:0071461	cellular response to redox state

Cellular Component

GO:0005615	extracellular space
GO:0005739	mitochondrion
GO:0005765	lysosomal membrane
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2177651

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR000742 Epidermal growth factor-like domain
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003961 Fibronectin, type III

PFAM