Version 5.4
Mus musculus Protein: Slc13a1
Summary
InnateDB Protein IDBP-129940.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc13a1
Protein Name solute carrier family 13 (sodium/sulfate symporters), member 1
Synonyms AI314066; AI987826; Nas1; NaSi-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000031713
InnateDB Gene IDBG-129938 (Slc13a1)
Protein Structure
UniProt Annotation
Function Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in kidney and ileum, detected at lower levels in duodenum/jejunum and colon, and at very low levels in cecum, testis, adrenal and adipose tissues. Expression of isoform 2 is very low.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008271 secondary active sulfate transmembrane transporter activity
GO:0015382 sodium:sulfate symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0008272 sulfate transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902358 sulfate transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1859937
InterPro IPR001898 Sodium/sulphate symporter
PFAM PF00939
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JHI4
PhosphoSite PhosphoSite-Q9JHI4
TrEMBL Q9JLA8
UniProt Splice Variant
Entrez Gene 55961
UniGene Mm.415741
RefSeq NP_062354
MGI ID
MGI Symbol Slc13a1
OMIM
CCDS CCDS19940
HPRD
IMGT
EMBL AF199365 AF199366 AF199380 AF200305 AF200306 AF200307 AF200308 AF200309 AF200310 AF200311 AF200312 AF200313 AF200314 AF200315 AF200316 AF200317 AF200318 AF200319 AK019876 BC022672 BC049981 CH466533
GenPept AAF64648 AAF64649 AAF64650 AAF65231 AAH22672 AAH49981 EDL13827

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca