Version 5.4
Mus musculus Protein: Xab2
Summary
InnateDB Protein IDBP-130122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xab2
Protein Name XPA binding protein 2
Synonyms 0610041O14Rik; AV025587;
Species Mus musculus
Ensembl Protein ENSMUSP00000019614
InnateDB Gene IDBG-130120 (Xab2)
Protein Structure
UniProt Annotation
Function Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Detected in the splicing complex carrying pre-mRNA. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0001824 blastocyst development
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006351 transcription, DNA-templated
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0071013 catalytic step 2 spliceosome
Protein Structure and Domains
PDB ID MGI:1914689
InterPro IPR003107 RNA-processing protein, HAT helix
IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF02184
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00386
SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCD2
PhosphoSite PhosphoSite-Q9DCD2
TrEMBL
UniProt Splice Variant
Entrez Gene 67439
UniGene Mm.399588
RefSeq NP_080432
MGI ID
MGI Symbol Xab2
OMIM
CCDS CCDS22065
HPRD
IMGT
EMBL AK002890 AK008628 BC021341
GenPept AAH21341 BAB22435 BAB25790

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca