Mus musculus Protein: Cd248
Summary
InnateDB Protein IDBP-130733.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd248
Protein Name CD248 antigen, endosialin
Synonyms 2610111G01Rik; AI842296; Cd164l1; Tem1;
Species Mus musculus
Ensembl Protein ENSMUSP00000070847
InnateDB Gene IDBG-130731 (Cd248)
Protein Structure
UniProt Annotation
Function May play a role in angiogenesis or vascular function. {ECO:0000269PubMed:11489895}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in cell lines derived from endothelial cells, embryonic fibroblasts and preadipocytes. {ECO:0000269PubMed:11489895}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0016477 cell migration
GO:0048535 lymph node development
GO:0060033 anatomical structure regression
GO:2000353 positive regulation of endothelial cell apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1917695
InterPro IPR000742 Epidermal growth factor-like domain
IPR001304 C-type lectin
IPR001881 EGF-like calcium-binding domain
IPR016187 C-type lectin fold
PFAM PF00008
PF00059
PF07645
PRINTS
PIRSF
SMART SM00181
SM00034
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91V98
PhosphoSite PhosphoSite-Q91V98
TrEMBL
UniProt Splice Variant
Entrez Gene 70445
UniGene Mm.29597
RefSeq NP_473383
MGI ID
MGI Symbol Cd248
OMIM
CCDS CCDS29448
HPRD
IMGT
EMBL AF378758 AF388572 AF388573 AK144655 BC046318
GenPept AAH46318 AAK84664 AAK84665 AAL11995 BAE25992