Mus musculus Protein: Fam105b
Summary
InnateDB Protein IDBP-131481.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam105b
Protein Name family with sequence similarity 105, member B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057893
InnateDB Gene IDBG-131479 (Fam105b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0002040 sprouting angiogenesis
GO:0006508 proteolysis
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:0060070 canonical Wnt signaling pathway
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:1990108 protein linear deubiquitination
Cellular Component
GO:0005737 cytoplasm
GO:0071797 LUBAC complex
Protein Structure and Domains
PDB ID MGI:3577015
InterPro IPR019400 Peptidase C65, otubain
IPR023235 FAM105
IPR023236 FAM105A
IPR023237 FAM105B
PFAM PF10275
PRINTS PR02055
PR02056
PR02057
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UCV8
PhosphoSite PhosphoSite-Q3UCV8
TrEMBL
UniProt Splice Variant
Entrez Gene 432940
UniGene Mm.309164
RefSeq NP_001013814
MGI ID
MGI Symbol Otulin
OMIM
CCDS CCDS49586
HPRD
IMGT
EMBL AK134955 AK150371 BC028541 BC087945 GL456173
GenPept AAH28541 AAH87945 BAE22354 BAE29504