InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp6v1f

Summary

InnateDB Protein

IDBP-131740.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp6v1f

Protein Name

ATPase, H+ transporting, lysosomal V1 subunit F

Synonyms

1110004G16Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004396

InnateDB Gene

IDBG-131738 (Atp6v1f)

Protein Structure

UniProt Annotation

Function

Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042625	ATPase activity, coupled to transmembrane movement of ions
GO:0046961	proton-transporting ATPase activity, rotational mechanism

Biological Process

GO:0015991	ATP hydrolysis coupled proton transport
GO:0034220	ion transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0033180	proton-transporting V-type ATPase, V1 domain
GO:0070062	extracellular vesicular exosome