Version 5.4
Mus musculus Protein: Pmm2
Summary
InnateDB Protein IDBP-131771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pmm2
Protein Name phosphomannomutase 2
Synonyms AI585868; C86848;
Species Mus musculus
Ensembl Protein ENSMUSP00000023396
InnateDB Gene IDBG-131769 (Pmm2)
Protein Structure
UniProt Annotation
Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004615 phosphomannomutase activity
Biological Process
GO:0008152 metabolic process
GO:0009298 GDP-mannose biosynthetic process
GO:0019307 mannose biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0043025 neuronal cell body
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1859214
InterPro IPR005002 Eukaryotic phosphomannomutase
IPR006379 HAD-superfamily hydrolase, subfamily IIB
IPR023214 HAD-like domain
PFAM PF03332
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z2M7
PhosphoSite PhosphoSite-Q9Z2M7
TrEMBL Q9DCE3
UniProt Splice Variant
Entrez Gene 54128
UniGene Mm.9699
RefSeq NP_058577
MGI ID
MGI Symbol Pmm2
OMIM
CCDS CCDS27941
HPRD
IMGT
EMBL AF043514 AK002858 AK005074 AK134850 AK145402 AK149116 BC046325 BC094448 CH466521
GenPept AAD02276 AAH46325 AAH94448 BAB22411 BAB23798 BAE22311 BAE26415 BAE28741 EDK97294

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca