InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Car3

Summary

InnateDB Protein

IDBP-132019.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Car3

Protein Name

carbonic anhydrase 3

Synonyms

BB219044; Ca3; Car-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029076

InnateDB Gene

IDBG-132017 (Car3)

Protein Structure

UniProt Annotation

Function

Reversible hydration of carbon dioxide.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity. {ECO:0000269PubMed:1922100}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004089	carbonate dehydratase activity
GO:0008270	zinc ion binding
GO:0016151	nickel cation binding

Biological Process

GO:0006730	one-carbon metabolic process
GO:0006979	response to oxidative stress
GO:0045471	response to ethanol

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

MGI:88270

InterPro

IPR001148 Alpha carbonic anhydrase

PFAM

PF00194

PRINTS

PIRSF

SMART

SM01057

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P16015

PhosphoSite

PhosphoSite-P16015

TrEMBL

UniProt Splice Variant

Entrez Gene

12350

UniGene

RefSeq

NP_031632

MGI ID

MGI Symbol

Car3

OMIM

CCDS

CCDS17250

HPRD

IMGT

EMBL

AF294983 AF294984 AF294985 AF294986 AF294987 AF294988 BC011129 M27796

GenPept

AAA37355 AAG22029 AAH11129