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InnateDB Protein
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IDBP-132468.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fhl5
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Protein Name
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four and a half LIM domains 5
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Synonyms
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1700027G07Rik; Act;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000029922
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InnateDB Gene
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IDBG-132466 (Fhl5)
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Protein Structure
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| Function |
May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation- independent manner (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Nucleus {ECO:0000269PubMed:10086359}. Note=Nuclei of round and elongated spermatids.
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| Disease Associations |
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| Tissue Specificity |
Testis-specific, temporal expression is coordinated with CREM. {ECO:0000269PubMed:10086359}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
9 [view]
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Molecular Function |
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| Biological Process |
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GO:0006351
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transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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| Cellular Component |
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| PDB ID |
MGI:1913192
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| InterPro |
IPR001781
Zinc finger, LIM-type
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| PFAM |
PF00412
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| PRINTS |
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| PIRSF |
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| SMART |
SM00132
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9WTX7
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| PhosphoSite |
PhosphoSite-Q9WTX7
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
57756
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| UniGene |
Mm.87325
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| RefSeq |
NP_067293
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| MGI ID |
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| MGI Symbol |
Fhl5
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| OMIM |
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| CCDS |
CCDS18009
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| HPRD |
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| IMGT |
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| EMBL |
AF083394
AK006414
BC048473
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| GenPept |
AAD23916
AAH48473
BAB24576
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Version 5.4