Mus musculus Protein: Gpr17
Summary
InnateDB Protein IDBP-133210.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr17
Protein Name G protein-coupled receptor 17
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000063670
InnateDB Gene IDBG-133208 (Gpr17)
Protein Structure
UniProt Annotation
Function Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3584514
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR003912 Protease-activated receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
PFAM PF00001
PF10320
PF10323
PRINTS PR00237
PR01428
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NS65
PhosphoSite PhosphoSite-Q6NS65
TrEMBL
UniProt Splice Variant
Entrez Gene 574402
UniGene Mm.391108
RefSeq NP_001020552
MGI ID
MGI Symbol Gpr17
OMIM
CCDS CCDS29114
HPRD
IMGT
EMBL AY255543 BC070439
GenPept AAH70439 AAO85055