InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sdc2

Summary

InnateDB Protein

IDBP-133234.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sdc2

Protein Name

syndecan 2

Synonyms

4833414L08Rik; AA960457; Hspg1; Synd2; syndecan-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022871

InnateDB Gene

IDBG-133232 (Sdc2)

Protein Structure

UniProt Annotation

Function

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis. {ECO:0000269PubMed:21555464}.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Preferential expression in cells of mesenchymal origin.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0030165	PDZ domain binding

Biological Process

GO:0001666	response to hypoxia
GO:0031000	response to caffeine
GO:0042060	wound healing
GO:0048813	dendrite morphogenesis
GO:0048814	regulation of dendrite morphogenesis