Version 5.4
| Mus musculus Protein: Tnfrsf17 | |||||||
|---|---|---|---|---|---|---|---|
| Summary | |||||||
| InnateDB Protein | IDBP-133359.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Tnfrsf17 | ||||||
| Protein Name | tumor necrosis factor receptor superfamily, member 17 | ||||||
| Synonyms | BCM; BCMA; Tnfrsf13; Tnfrsf13a; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000023140 | ||||||
| InnateDB Gene | IDBG-133357 (Tnfrsf17) | ||||||
| Protein Structure |
|
||||||
| UniProt Annotation | |||||||
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Detected in spleen, thymus, bone marrow and heart, and at lower levels in kidney and lung. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
|
||||||
| Gene Ontology | |||||||
Molecular Function |
|
||||||
| Biological Process |
|
||||||
| Cellular Component |
|
||||||
| Protein Structure and Domains | |||||||
| PDB ID | MGI:1343050 | ||||||
| InterPro |
IPR015337
BCMA, TALL-1 binding IPR022320 Tumour necrosis factor receptor 17 IPR022338 Tumour necrosis factor receptor 13C |
||||||
| PFAM |
PF09257
|
||||||
| PRINTS |
PR01967
PR01964 |
||||||
| PIRSF |
PIRSF011859
|
||||||
| SMART | |||||||
| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | O88472 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 21935 | ||||||
| UniGene | Mm.12935 | ||||||
| RefSeq | NP_035738 | ||||||
| MGI ID | |||||||
| MGI Symbol | Tnfrsf17 | ||||||
| OMIM | |||||||
| CCDS | CCDS27962 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AF061505 AK020247 BC027519 | ||||||
| GenPept | AAC23799 AAH27519 BAB32038 | ||||||