InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Matn2

Summary

InnateDB Protein

IDBP-133600.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Matn2

Protein Name

matrilin 2

Synonyms

Crtm2; matrilin-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022947

InnateDB Gene

IDBG-133598 (Matn2)

Protein Structure

UniProt Annotation

Function

Involved in matrix assembly. {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Detected in a variety of organs, including calvaria, uterus, heart and brain, as well as fibroblast and osteoblast cell lines.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001764	neuron migration
GO:0007411	axon guidance
GO:0008347	glial cell migration
GO:0031104	dendrite regeneration
GO:0031175	neuron projection development
GO:0048678	response to axon injury

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005604	basement membrane

Protein Structure and Domains

PDB ID

MGI:109613

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002035 von Willebrand factor, type A
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR019466 Matrilin, coiled-coil trimerisation domain

PFAM

PF00008
PF07645
PF00092
PF10393

PRINTS

PIRSF

SMART

SM00181
SM00179
SM00327

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O08746