Mus musculus Protein: Prpf18
Summary
InnateDB Protein IDBP-133773.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prpf18
Protein Name PRP18 pre-mRNA processing factor 18 homolog (yeast)
Synonyms 2810441A10Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000041428
InnateDB Gene IDBG-133771 (Prpf18)
Protein Structure
UniProt Annotation
Function Participates in the second step of pre-mRNA splicing. {ECO:0000250}.
Subcellular Localization Nucleus speckle {ECO:0000250}. Note=Colocalizes with spliceosomal snRNPs. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019870 potassium channel inhibitor activity
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005575 cellular_component
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID MGI:1914479
InterPro IPR003648 Splicing factor motif
IPR004098 Prp18
IPR014906 Pre-mRNA processing factor 4 (PRP4)-like
PFAM PF02840
PF08799
PRINTS
PIRSF
SMART SM00500
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BM39
PhosphoSite PhosphoSite-Q8BM39
TrEMBL Q3V3Z1
UniProt Splice Variant
Entrez Gene 67229
UniGene Mm.38529
RefSeq NP_080321
MGI ID
MGI Symbol Prpf18
OMIM
CCDS CCDS15657
HPRD
IMGT
EMBL AK028921 AK035073 AK036668 AK135707 AK135890 AK139720 AK161550 BC004573 BC058631
GenPept AAH04573 AAH58631 BAC28933 BAC29527 BAE22619 BAE22717 BAE24112 BAE36457 BAE43267