Version 5.4
Mus musculus Protein: Ecd
Summary
InnateDB Protein IDBP-134469.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ecd
Protein Name ecdysoneless homolog (Drosophila)
Synonyms 5730461K03Rik; Hsgt1;
Species Mus musculus
Ensembl Protein ENSMUSP00000022344
InnateDB Gene IDBG-134467 (Ecd)
Protein Structure
UniProt Annotation
Function Novel regulator of p53 stability and function (By similarity). May also be a transcriptional activator required for the expression of glycolytic genes. {ECO:0000250}.
Subcellular Localization Cytoplasm. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008283 cell proliferation
GO:2000045 regulation of G1/S transition of mitotic cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1917851
InterPro IPR010770 SGT1
PFAM PF07093
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CS74
PhosphoSite PhosphoSite-Q9CS74
TrEMBL
UniProt Splice Variant
Entrez Gene 70601
UniGene Mm.452334
RefSeq NP_081751
MGI ID
MGI Symbol Ecd
OMIM
CCDS CCDS26842
HPRD
IMGT
EMBL AK028664 BC013470
GenPept AAH13470 BAC26054

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca