InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Msc

Summary

InnateDB Protein

IDBP-134648.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Msc

Protein Name

musculin

Synonyms

bHLHa22; MyoR;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027062

InnateDB Gene

IDBG-134646 (Msc)

Protein Structure

UniProt Annotation

Function

Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0046983	protein dimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0014707	branchiomeric skeletal muscle development
GO:0060021	palate development
GO:0060539	diaphragm development