Version 5.4
Mus musculus Protein: Tmco3
Summary
InnateDB Protein IDBP-135024.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmco3
Protein Name transmembrane and coiled-coil domains 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000040347
InnateDB Gene IDBG-135022 (Tmco3)
Protein Structure
UniProt Annotation
Function Probable Na(+)/H(+) antiporter. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0015299 solute:proton antiporter activity
Biological Process
GO:0006812 cation transport
GO:0008150 biological_process
GO:0055085 transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2444946
InterPro IPR006153 Cation/H+ exchanger
PFAM PF00999
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BH01
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 234076
UniGene Mm.219813
RefSeq NP_758486
MGI ID
MGI Symbol Tmco3
OMIM
CCDS CCDS40231
HPRD
IMGT
EMBL AK033499 AK046065 AK049974 AK088866 AK148252 BC026890 BC039955 BC053487
GenPept AAH26890 AAH39955 AAH53487 BAC28322 BAC32588 BAC34013 BAC40623 BAE28438

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca