InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ispd

Summary

InnateDB Protein

IDBP-135513.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ispd

Protein Name

isoprenoid synthase domain containing

Synonyms

4930579E17Rik; AV040780;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000061646

InnateDB Gene

IDBG-135511 (Ispd)

Protein Structure

UniProt Annotation

Function

Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0016779	nucleotidyltransferase activity

Biological Process

GO:0006486	protein glycosylation
GO:0007411	axon guidance
GO:0008299	isoprenoid biosynthetic process
GO:0035269	protein O-linked mannosylation

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1923097

InterPro

IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IPR029044 Nucleotide-diphospho-sugar transferases

PFAM

PF01128

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5RJG7

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

75847

UniGene

Mm.473967

RefSeq

NP_848744

MGI ID

MGI Symbol

Ispd

OMIM

CCDS

CCDS49051

HPRD

IMGT

EMBL

AK039004 AK043122 AK045940 BC024061 BC086665 BC096030 BC118038

GenPept

AAH24061 AAH86665 AAH96030 AAI18039 BAC30199 BAC31463 BAC32538