InnateDB Protein
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IDBP-135627.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Meox2
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Protein Name
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mesenchyme homeobox 2
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Synonyms
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AI528662; Gax; Mox-2; Mox2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000043587
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InnateDB Gene
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IDBG-135625 (Meox2)
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Protein Structure
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Function |
Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}. Nucleus speckle {ECO:0000255PROSITE- ProRule:PRU00108}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000978
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RNA polymerase II core promoter proximal region sequence-specific DNA binding
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GO:0000980
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RNA polymerase II distal enhancer sequence-specific DNA binding
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GO:0001077
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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0001205
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RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0005515
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protein binding
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:103219
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InterPro |
IPR001356
Homeobox domain
IPR009057
Homeodomain-like
IPR020479
Homeodomain, metazoa
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PFAM |
PF00046
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PRINTS |
PR00024
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PIRSF |
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SMART |
SM00389
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TIGRFAMs |
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Modification |
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SwissProt |
P32443
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PhosphoSite |
PhosphoSite-P32443
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
17286
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UniGene |
Mm.341398
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RefSeq |
NP_032610
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MGI ID |
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MGI Symbol |
Meox2
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OMIM |
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CCDS |
CCDS25888
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HPRD |
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IMGT |
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EMBL |
AK028352
AK031152
AK142690
S79168
Z16406
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GenPept |
BAC25898
BAC27282
BAE25163
CAA78899
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