InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il20ra

Summary

InnateDB Protein

IDBP-136069.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il20ra

Protein Name

interleukin 20 receptor, alpha

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020185

InnateDB Gene

IDBG-136067 (Il20ra)

Protein Structure

UniProt Annotation

Function

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26 (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042015	interleukin-20 binding

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0045124	regulation of bone resorption
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway