InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pkhd1

Summary

InnateDB Protein

IDBP-136161.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Pkhd1

Protein Name

polycystic kidney and hepatic disease 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000085794

InnateDB Gene

IDBG-136157 (Pkhd1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001822	kidney development
GO:0006874	cellular calcium ion homeostasis
GO:0008284	positive regulation of cell proliferation
GO:0010824	regulation of centrosome duplication
GO:0032006	regulation of TOR signaling
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0042384	cilium assembly
GO:0043066	negative regulation of apoptotic process
GO:0051898	negative regulation of protein kinase B signaling
GO:0070372	regulation of ERK1 and ERK2 cascade

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0016324	apical plasma membrane
GO:0036064	ciliary basal body
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome
GO:0072372	primary cilium
GO:0072686	mitotic spindle

Protein Structure and Domains

PDB ID

MGI:2155808

InterPro

IPR002909 IPT domain
IPR006626 Parallel beta-helix repeat
IPR011050 Pectin lyase fold/virulence factor
IPR014756 Immunoglobulin E-set
IPR019316 G8 domain

PFAM

PF01833
PF10162

PRINTS

PIRSF

SMART

SM00429
SM00710

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite