InnateDB Protein
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IDBP-136433.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Agpat4
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Protein Name
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1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
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Synonyms
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1500003P24Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000024594
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InnateDB Gene
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IDBG-136431 (Agpat4)
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Protein Structure
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Function |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. {ECO:0000269PubMed:15367102}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed at a high levels in the brain, at intermediate or low levels in skeletal muscles, gut, kidney, spleen and lung. Barely detectable in heart and liver. {ECO:0000269PubMed:15367102}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003674
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molecular_function
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GO:0003841
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1-acylglycerol-3-phosphate O-acyltransferase activity
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GO:0016746
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transferase activity, transferring acyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915512
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InterPro |
IPR002123
Phospholipid/glycerol acyltransferase
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PFAM |
PF01553
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PRINTS |
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PIRSF |
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SMART |
SM00563
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K4X7
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PhosphoSite |
PhosphoSite-Q8K4X7
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TrEMBL |
E9Q6S5
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UniProt Splice Variant |
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Entrez Gene |
68262
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UniGene |
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RefSeq |
NP_080920
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MGI ID |
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MGI Symbol |
Agpat4
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OMIM |
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CCDS |
CCDS28389
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HPRD |
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IMGT |
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EMBL |
AC136921
AC163746
AF485269
AK005139
AK166917
BC047281
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GenPept |
AAH47281
AAM33375
BAB23837
BAE39115
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