InnateDB Protein
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IDBP-136495.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Atp6v1c1
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Protein Name
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ATPase, H+ transporting, lysosomal V1 subunit C1
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Synonyms
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1700025B18Rik; U13839;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000022904
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InnateDB Gene
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IDBG-136493 (Atp6v1c1)
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Protein Structure
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Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Abundant in brain, liver, kidney and testis. {ECO:0000269PubMed:12527205}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0008553
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hydrogen-exporting ATPase activity, phosphorylative mechanism
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GO:0015078
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hydrogen ion transmembrane transporter activity
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Biological Process |
GO:0015991
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ATP hydrolysis coupled proton transport
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Cellular Component |
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PDB ID |
MGI:1913585
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InterPro |
IPR004907
ATPase, V1 complex, subunit C
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PFAM |
PF03223
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z1G3
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PhosphoSite |
PhosphoSite-Q9Z1G3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
66335
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UniGene |
Mm.474086
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RefSeq |
NP_079770
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MGI ID |
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MGI Symbol |
Atp6v1c1
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OMIM |
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CCDS |
CCDS27439
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HPRD |
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IMGT |
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EMBL |
AB088407
AK075779
AK151237
BC010217
U13839
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GenPept |
AAC83084
AAH10217
BAC35953
BAC57953
BAE30229
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