Version 5.4
Homo sapiens Protein: NCAPH2
Summary
InnateDB Protein IDBP-13670.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPH2
Protein Name non-SMC condensin II complex, subunit H2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000299821
InnateDB Gene IDBG-13668 (NCAPH2)
Protein Structure
UniProt Annotation
Function Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:14532007}. Chromosome {ECO:0000269PubMed:14532007}. Note=Distributed along the arms of chromosomes assembled in vivo and in vitro.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0030261 chromosome condensation
Cellular Component
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR009378 Non-SMC condensin II complex, subunit H2-like
PFAM PF06278
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6IBW4
PhosphoSite PhosphoSite-Q6IBW4
TrEMBL
UniProt Splice Variant
Entrez Gene 29781
UniGene Hs.730607
RefSeq NP_001171940
HUGO HGNC:25071
OMIM 611230
CCDS CCDS54546
HPRD
IMGT
EMBL AL021682 BC000473 BC001509 BC001833 BC001937 BC009441 BC014939 CH471138 CR456604 U62317
GenPept AAB03345 AAH00473 AAH01509 AAH01833 AAH01937 AAH09441 AAH14939 CAA16670 CAG30490 EAW73552 EAW73554 EAW73556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca