Version 5.4
Homo sapiens Protein: METTL22
Summary
InnateDB Protein IDBP-13740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METTL22
Protein Name methyltransferase like 22
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371345
InnateDB Gene IDBG-13738 (METTL22)
Protein Structure
UniProt Annotation
Function Protein N-lysine methyltransferase. In vitro methylates KIN. {ECO:0000269PubMed:23349634}.
Subcellular Localization Nucleus {ECO:0000269PubMed:23349634}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR019410 Nicotinamide N-methyltransferase-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF10294
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BUU2
PhosphoSite PhosphoSite-Q9BUU2
TrEMBL H3BTR2
UniProt Splice Variant
Entrez Gene 79091
UniGene
RefSeq NP_077014
HUGO HGNC:28368
OMIM 615261
CCDS CCDS10533
HPRD 08324
IMGT
EMBL AC007224 AC138420 AK022495 AK315383 AY203956 BC001908 CH471112
GenPept AAH01908 AAP34479 BAB14058 BAG37776 EAW85210 EAW85211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca