InnateDB Protein
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IDBP-137486.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tcp1
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Protein Name
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t-complex protein 1
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Synonyms
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AI528772; c-cpn; CCT; Cct1; Ccta; p63; Tcp-1; Tp63; TRic;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000086418
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InnateDB Gene
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IDBG-137484 (Tcp1)
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Protein Structure
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Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 94 interaction(s) predicted by orthology.
Experimentally validated |
Total |
27
[view]
|
Protein-Protein |
23
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
2
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
94 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:98535
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InterPro |
IPR002423
Chaperonin Cpn60/TCP-1
IPR017998
Chaperone tailless complex polypeptide 1 (TCP-1)
IPR027409
GroEL-like apical domain
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PFAM |
PF00118
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PRINTS |
PR00304
|
PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P11983
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PhosphoSite |
PhosphoSite-P11983
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TrEMBL |
Q6LBL9
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UniProt Splice Variant |
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Entrez Gene |
21454
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UniGene |
Mm.229342
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RefSeq |
NP_001277641
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MGI ID |
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MGI Symbol |
Tcp1
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OMIM |
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CCDS |
CCDS70760
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HPRD |
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IMGT |
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EMBL |
AK149611
AK149755
AK151068
AK151445
AK152641
AK153430
AK165665
AK166828
AK166966
AK167529
BC003809
D10606
D90344
M12899
M20130
S46763
X61214
X61217
X61219
X61220
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GenPept |
AAA40337
AAA40338
AAB23855
AAH03809
BAA01461
BAA14356
BAE28989
BAE29063
BAE30084
BAE30407
BAE31381
BAE31988
BAE38327
BAE39052
BAE39149
BAE39599
CAA43528
CAA43531
CAA43533
CAA43534
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