InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dcaf12

Summary

InnateDB Protein

IDBP-137620.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dcaf12

Protein Name

DDB1 and CUL4 associated factor 12

Synonyms

1500001L20Rik; 5830424K06Rik; AA420338; AI851081; Wdr40a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030145

InnateDB Gene

IDBG-137618 (Dcaf12)

Protein Structure

UniProt Annotation

Function

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0016567	protein ubiquitination

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0080008	Cul4-RING E3 ubiquitin ligase complex

Protein Structure and Domains

PDB ID

MGI:1916220

InterPro

IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain

PFAM

PF00400

PRINTS

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BGZ3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

68970

UniGene

Mm.474754

RefSeq

NP_081169

MGI ID

MGI Symbol

Dcaf12

OMIM

CCDS

CCDS18059

HPRD

IMGT

EMBL

AK005099 AK030173 AK031089 AK087517 AK090028 AK173289 AL807823 BC023852

GenPept

AAH23852 BAB23817 BAC26822 BAC27247 BAC39908 BAC41053 BAD32567 CAM20984