Version 5.4
| Mus musculus Protein: Lrrc17 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-138061.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Lrrc17 | ||||||
| Protein Name | leucine rich repeat containing 17 | ||||||
| Synonyms | 37kDa; 4833425M04Rik; 6130400C22Rik; P37nb; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000038569 | ||||||
| InnateDB Gene | IDBG-138059 (Lrrc17) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors. {ECO:0000269PubMed:19336404}. | ||||||
| Subcellular Localization | Secreted, extracellular space {ECO:0000269PubMed:19336404}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expressed in osteoblasts, spleen, lung and heart. {ECO:0000269PubMed:19336404}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:1921761 | ||||||
| InterPro |
IPR000483
Cysteine-rich flanking region, C-terminal IPR001611 Leucine-rich repeat IPR003591 Leucine-rich repeat, typical subtype |
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| PFAM |
PF01463
PF00560 PF13504 PF13855 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00082
SM00369 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q9CXD9 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 74511 | ||||||
| UniGene | Mm.450853 | ||||||
| RefSeq | NP_083253 | ||||||
| MGI ID | |||||||
| MGI Symbol | Lrrc17 | ||||||
| OMIM | |||||||
| CCDS | CCDS51428 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK018071 BC030317 | ||||||
| GenPept | AAH30317 BAB31060 | ||||||