Version 5.4
Mus musculus Protein: Ndufa1
Summary
InnateDB Protein IDBP-138846.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufa1
Protein Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
Synonyms 1810049F12Rik; MWFE;
Species Mus musculus
Ensembl Protein ENSMUSP00000016571
InnateDB Gene IDBG-138844 (Ndufa1)
Protein Structure
UniProt Annotation
Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID MGI:1929511
InterPro IPR017384 NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
PFAM
PRINTS
PIRSF PIRSF038095
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35683
PhosphoSite PhosphoSite-O35683
TrEMBL Q545K0
UniProt Splice Variant
Entrez Gene 54405
UniGene
RefSeq NP_062316
MGI ID
MGI Symbol Ndufa1
OMIM
CCDS CCDS40928
HPRD
IMGT
EMBL AK007840 BC024364 CH466645 CT010398 Y07708
GenPept AAH24364 BAB25297 CAA68977 CAJ18604 EDL28994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca