Version 5.4
Mus musculus Protein: Plxdc2
Summary
InnateDB Protein IDBP-138898.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plxdc2
Protein Name plexin domain containing 2
Synonyms 1200007L24Rik; 5430431D22Rik; AI646728; AU022916; AV231634; Tem7r;
Species Mus musculus
Ensembl Protein ENSMUSP00000028081
InnateDB Gene IDBG-138896 (Plxdc2)
Protein Structure
UniProt Annotation
Function May play a role in tumor angiogenesis. {ECO:0000269PubMed:11559528}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. {ECO:0000269PubMed:11559528}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1914698
InterPro IPR002165 Plexin
IPR016201 Plexin-like fold
PFAM PF01437
PRINTS
PIRSF
SMART SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DC11
PhosphoSite PhosphoSite-Q9DC11
TrEMBL
UniProt Splice Variant
Entrez Gene 67448
UniGene Mm.437344
RefSeq NP_080438
MGI ID
MGI Symbol Plxdc2
OMIM
CCDS CCDS15705
HPRD
IMGT
EMBL AF378761 AK004640 AK154921 BC057881
GenPept AAH57881 AAL11998 BAB23431 BAE32927

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca