InnateDB Protein
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IDBP-13923.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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AHSA1
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Protein Name
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AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
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Synonyms
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AHA1; C14orf3; p38;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000216479
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InnateDB Gene
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IDBG-13921 (AHSA1)
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Protein Structure
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Function |
Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000269PubMed:11554768}. Endoplasmic reticulum {ECO:0000269PubMed:11554768}. Note=May transiently interact with the endoplasmic reticulum.
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Disease Associations |
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Tissue Specificity |
Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta. {ECO:0000269PubMed:11554768}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
39
[view]
|
Protein-Protein |
37
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR013538
Activator of Hsp90 ATPase homologue 1-like
IPR015310
Activator of Hsp90 ATPase, N-terminal
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PFAM |
PF08327
PF09229
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PRINTS |
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PIRSF |
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SMART |
SM01000
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TIGRFAMs |
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Modification |
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SwissProt |
O95433
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PhosphoSite |
PhosphoSite-O95433
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TrEMBL |
G3V438
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UniProt Splice Variant |
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Entrez Gene |
10598
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UniGene |
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RefSeq |
NP_036243
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HUGO |
HGNC:1189
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OMIM |
608466
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CCDS |
CCDS9863
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HPRD |
09768
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IMGT |
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EMBL |
AF111168
AF161440
AF164791
AJ243310
AK313824
BC000321
BC007398
CH471061
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GenPept |
AAD09623
AAF29000
AAF80755
AAH00321
AAH07398
BAG36559
CAB45684
EAW81291
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