InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arg1

Summary

InnateDB Protein

IDBP-139460.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arg1

Protein Name

arginase, liver

Synonyms

AI; AI256583; Arg-1; PGIF;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020161

InnateDB Gene

IDBG-139458 (Arg1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	5 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004053	arginase activity
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0030145	manganese ion binding
GO:0046872	metal ion binding

Biological Process

GO:0000050	urea cycle
GO:0001889	liver development
GO:0001938	positive regulation of endothelial cell proliferation
GO:0006525	arginine metabolic process
GO:0007565	female pregnancy
GO:0009611	response to wounding
GO:0009635	response to herbicide
GO:0010042	response to manganese ion
GO:0010043	response to zinc ion
GO:0010269	response to selenium ion
GO:0010963	regulation of L-arginine import
GO:0014075	response to amine
GO:0030324	lung development
GO:0032496	response to lipopolysaccharide
GO:0032964	collagen biosynthetic process
GO:0033189	response to vitamin A
GO:0033197	response to vitamin E
GO:0042493	response to drug
GO:0043200	response to amino acid
GO:0043434	response to peptide hormone
GO:0046686	response to cadmium ion
GO:0048545	response to steroid hormone
GO:0048678	response to axon injury
GO:0051597	response to methylmercury
GO:0060056	mammary gland involution
GO:0060135	maternal process involved in female pregnancy
GO:0070207	protein homotrimerization
GO:0070301	cellular response to hydrogen peroxide
GO:0071222	cellular response to lipopolysaccharide
GO:0071353	cellular response to interleukin-4
GO:0071377	cellular response to glucagon stimulus
GO:0071549	cellular response to dexamethasone stimulus
GO:0071560	cellular response to transforming growth factor beta stimulus

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0070062	extracellular vesicular exosome