InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tomm7

Summary

InnateDB Protein

IDBP-139920.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tomm7

Protein Name

translocase of outer mitochondrial membrane 7 homolog (yeast)

Synonyms

1110020J08Rik; AW047273; Tom7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030851

InnateDB Gene

IDBG-139918 (Tomm7)

Protein Structure

UniProt Annotation

Function

Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0030150	protein import into mitochondrial matrix

Cellular Component

GO:0005739	mitochondrion
GO:0005742	mitochondrial outer membrane translocase complex
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1913419

InterPro

IPR012621 Mitochondrial import receptor subunit TOM7

PFAM

PF08038

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D173

PhosphoSite

PhosphoSite-Q9D173

TrEMBL

UniProt Splice Variant

Entrez Gene

66169

UniGene

RefSeq

NP_079670

MGI ID

MGI Symbol

Tomm7

OMIM

CCDS

CCDS39026

HPRD

IMGT

EMBL

AK003864 BC055352

GenPept

AAH55352 BAB23046