Version 5.4
Mus musculus Protein: Fam126a
Summary
InnateDB Protein IDBP-139966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam126a
Protein Name family with sequence similarity 126, member A
Synonyms AB030242; Drctnnb1a;
Species Mus musculus
Ensembl Protein ENSMUSP00000030849
InnateDB Gene IDBG-139962 (Fam126a)
Protein Structure
UniProt Annotation
Function May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}.
Disease Associations
Tissue Specificity Predominantly expressed in the central nervous system, where it is found in neurons but not in myelinating cells. Lower abundance is observed in peripheral neurons, where it is detectable only at early postnatal ages. {ECO:0000269PubMed:22461884}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2149839
InterPro IPR018619 Hyccin
PFAM PF09790
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P9N1
PhosphoSite PhosphoSite-Q6P9N1
TrEMBL
UniProt Splice Variant
Entrez Gene 84652
UniGene Mm.488258
RefSeq NP_444320
MGI ID
MGI Symbol Fam126a
OMIM
CCDS CCDS19113
HPRD
IMGT
EMBL AB030242 BC056381 BC060692
GenPept AAH56381 AAH60692 BAB39850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca