Version 5.4
Mus musculus Protein: Selm
Summary
InnateDB Protein IDBP-139985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Selm
Protein Name selenoprotein M
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000092041
InnateDB Gene IDBG-139983 (Selm)
Protein Structure
UniProt Annotation
Function May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000269PubMed:11839807}. Endoplasmic reticulum {ECO:0000305PubMed:11839807}. Golgi apparatus {ECO:0000305PubMed:11839807}. Note=Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
Disease Associations
Tissue Specificity Widely expressed. Highly expressed in brain. {ECO:0000269PubMed:11839807}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0010269 response to selenium ion
GO:0035264 multicellular organism growth
GO:0035934 corticosterone secretion
GO:0042445 hormone metabolic process
GO:0060612 adipose tissue development
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:2149786
InterPro IPR012336 Thioredoxin-like fold
IPR014912 Sep15/SelM redox
PFAM PF13098
PF13192
PF13462
PF13905
PF08806
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VHC3
PhosphoSite PhosphoSite-Q8VHC3
TrEMBL
UniProt Splice Variant
Entrez Gene 114679
UniGene Mm.403763
RefSeq NP_444497
MGI ID 2A2P
MGI Symbol Selm
OMIM
CCDS CCDS24365
HPRD
IMGT
EMBL AK018791 AK035312 AK046034 AY043488 BC019742 BC147332 BC147333
GenPept AAH19742 AAI47333 AAI47334 AAK95398 BAC29028 BAE43252 BAE43327

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca