InnateDB Protein
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IDBP-140426.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Etl4
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Protein Name
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enhancer trap locus 4
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000066170
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InnateDB Gene
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IDBG-140422 (Etl4)
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Protein Structure
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Function |
Required for normal development of intervertebral disks. {ECO:0000269PubMed:16204209}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:16204209}.
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in the notochord and mesonephros during embryogenesis as well as in other areas such as the epithalamus sulcus, lens vesicle, inner retinal layer, heart, hepatic primordial surface, infundibulum, surface ectoderm, hind gut and limb bud mesenchyme. In adults, expressed in a range of tissues including the nucleus pulposus, corpus callosum, kidney, cardiac muscle, Sertoli cells and hair follicles. {ECO:0000269PubMed:16204209}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
8 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:95454
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InterPro |
IPR022782
Actin interacting protein 3, C-terminal
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PFAM |
PF03915
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A2AQ25
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PhosphoSite |
PhosphoSite-BAC41473
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TrEMBL |
Q8BHR1
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UniProt Splice Variant |
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Entrez Gene |
208618
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UniGene |
Mm.397986
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RefSeq |
NP_001171102
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MGI ID |
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MGI Symbol |
Etl4
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB093289
AB125594
AB125595
AK052020
AK052733
AK054453
AL844538
AL845528
AL928572
AL929100
BC026657
BC050016
BX276179
BX571892
BX649224
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GenPept |
AAH26657
AAH50016
BAC34833
BAC35121
BAC35783
BAC41473
BAD14929
BAD14930
CAM19813
CAM19814
CAM19815
CAM24302
CAM24303
CAM24304
CAM24306
CAM24307
CAM24308
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