InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dst

Summary

InnateDB Protein

IDBP-140940.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Dst

Protein Name

dystonin

Synonyms

2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; Bpag; Bpag1; BPAG1-n; dt; Macf2; mKIAA0728; nmf203; nmf339;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095392

InnateDB Gene

IDBG-140932 (Dst)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005178	integrin binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0008022	protein C-terminus binding
GO:0042803	protein homodimerization activity
GO:0051010	microtubule plus-end binding

Biological Process

GO:0007050	cell cycle arrest
GO:0007409	axonogenesis
GO:0008090	retrograde axon cargo transport
GO:0009611	response to wounding
GO:0030011	maintenance of cell polarity
GO:0031110	regulation of microtubule polymerization or depolymerization
GO:0031122	cytoplasmic microtubule organization
GO:0031581	hemidesmosome assembly
GO:0048870	cell motility

Cellular Component

GO:0005634	nucleus
GO:0005856	cytoskeleton
GO:0015629	actin cytoskeleton
GO:0015630	microtubule cytoskeleton
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030056	hemidesmosome
GO:0031252	cell leading edge
GO:0035371	microtubule plus-end
GO:0060053	neurofilament cytoskeleton

Protein Structure and Domains

PDB ID

MGI:104627

InterPro

IPR001101 Plectin repeat
IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR002048 EF-hand domain
IPR003108 Growth-arrest-specific protein 2 domain
IPR009071 High mobility group box domain
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM