Version 5.4
Homo sapiens Protein: FAM57A
Summary
InnateDB Protein IDBP-14122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM57A
Protein Name family with sequence similarity 57, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000312017
InnateDB Gene IDBG-14120 (FAM57A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Highly expressed in pancreas. Detected at intermediate levels in heart, placenta and kidney, and at low levels in brain, liver and skeletal muscle. Not detected in normal lung. {ECO:0000269PubMed:12270127}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006634 TRAM/LAG1/CLN8 homology domain
PFAM PF03798
PRINTS
PIRSF
SMART SM00724
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TBR7
PhosphoSite PhosphoSite-Q8TBR7
TrEMBL
UniProt Splice Variant
Entrez Gene 79850
UniGene Hs.660157
RefSeq NP_079068
HUGO HGNC:29646
OMIM 611627
CCDS CCDS10996
HPRD 13096
IMGT
EMBL AF477201 AK025935 AK292065 BC009729 BC026023 CH471108
GenPept AAH09729 AAH26023 AAM90843 BAB15286 BAF84754 EAW90655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca