InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc25a31

Summary

InnateDB Protein

IDBP-141239.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc25a31

Protein Name

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31

Synonyms

1700034J06Rik; Ant4; Sfec;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000088723

InnateDB Gene

IDBG-141237 (Slc25a31)

Protein Structure

UniProt Annotation

Function

Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility. {ECO:0000269PubMed:17137571}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000250}. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity

Biological Process

GO:0055085

transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005929	cilium
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1920583

InterPro

IPR002067 Mitochondrial carrier protein
IPR002113 Adenine nucleotide translocator 1
IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain

PFAM

PF00153

PRINTS

PR00926
PR00927

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3V132